Litterature and presentations

Listed below is the most current litterature and presentations regarding the use of MR in RT presented by partners from the consortia. We strive to keep the list updated but this is an important topic meaning that there will always be a need for updates. If you feel there are publications, dissertations, presentations missing in this publications, please feel free to tell us!


Published papers


MR-OPERA: A Multicenter/Multivendor Validation of Magnetic Resonance Imaging-Only Prostate Treatment Planning Using Synthetic Computed Tomography ImagesEffect of gradient field nonlinearity distortions in MRI-based attenuation maps for PET reconstruction

Persson E, Gustafsson C, Nordström F, Sohlin M, Gunnlaugsson A, Petruson K, Rintelä N, Hed K, Blomqvist L, Zackrisson B, Nyholm T, Olsson LE, Siversson C, Jonsson J.
Int J Radiat Oncol Biol Phys. 2017 Jun 16

Registration free automatic identification of gold fiducial markers in MRI target delineation images for prostate radiotherapy.

Gustafsson C, Korhonen J, Persson E, Gunnlaugsson A, Nyholm T, Olsson LE. Med Phys. 2017 Aug 13

Effect of gradient field nonlinearity distortions in MRI-based attenuation maps for PET reconstruction

JA Lundman, A Johansson, J Olofsson, J Axelsson, A Larsson, T Nyholm
Physica Medica 35, 1-6

Assessment of dosimetric impact of system specific geometric distortion in an MRI only based radiotherapy workflow for prostate

C Gustafsson, F Nordström, E Persson, J Brynolfsson and L E Olsson. Phys. Med. Biol. 62 (2017) 2976–2989

Intensity-based dual model method for generation of synthetic CT images from standard T2-weighted MR images – Generalized technique for four different MR scanners

Koivula L, Kapanen M, Seppälä T, Collan J, Dowling J, Greer P, Gustafsson C, Gunnlaugsson A, Olsson LE, Wee L, Korhonen J.. Radiother Oncol. 2017 Oct 30. pii: S0167-8140(17)32651-8

Patient-induced susceptibility effects simulation in magnetic resonance imaging

JA Lundman, M Bylund, A Garpebring, CT Karlsson, T Nyholm
Physics and Imaging in Radiation Oncology 1, 41-45

A review of substitute CT generation for MRI-only radiation therapy

JM Edmund, T Nyholm
Radiation Oncology 12 (1), 28


A national approach for automated collection of standardized and population-based radiation therapy data in Sweden

T Nyholm, C Olsson, M Agrup, P Björk, T Björk-Eriksson, G Gagliardi, …
Radiotherapy and Oncology 119 (2), 344-350

EP-1913: National automated collection of standardised and population-based radiation therapy data in Sweden

T Nyholm, C Olsson, T Björk-Eriksson, G Gagliardi, A Gunnlaugsson, …
Radiotherapy and Oncology 119, S907-S908


SP-0128: MR-PET for radiation oncology: the implementation issues

T Nyholm
Radiotherapy and Oncology, S58

EP-1533: ICE-Studio-An Interactive visual research tool for image analysis

T Nyholm, M Berglund, P Brynolfsson, J Jonsson
Radiotherapy and Oncology 115, S837

Technical Note: MRI only prostate radiotherapy planning using the statistical decomposition algorithm

Carl Siversson, Fredrik Nordström, Terese Nilsson, Tufve Nyholm, Joakim Jonsson, Adalsteinn Gunnlaugsson and Lars E. Olsson
Medical Physics 42, 6090

Dose-volume histogram prediction using density estimation

JS Munter, J Sjölund

Physics in medicine and biology 60 (17), 6923

Accuracy of inverse treatment planning on substitute CT images derived from MR data for brain lesions

JH Jonsson, MM Akhtari, MG Karlsson, A Johansson, T Asklund, …

Radiation Oncology 10 (1),

Visual assessment of biliary excretion of Gd-EOB-DTPA in patients with suspected diffuse liver disease – a biopsy-verified prospective study.

Norén B, Dahlström N, Forsgren MF, Dahlqvist Leinhard O,  Kechagias S, Almer S, Wirell S, Smedby Ö, Lundberg P

Eur J Radiol Open, 2015 (2) 19-25.

Consistent intensity inhomogeneity correction in water-fat MRI

Andersson T, Romu T, Karlsson A, Norén B, Forsgren MF, Smedby O, Kechagias S, Almer S, Lundberg P, Borga M, Leinhard OD.

J Magn Reson Imaging. 2015 Aug;42(2):468-76. doi: 10.1002/jmri.24778. Epub 2014 Oct 30.



MRI in radiotherapy—Is it time to rethink the current radiotherapy fixation solutions?

T Nyholm, T Mullaney, LE Olsson, K Finnilä, B Zackrisson

Journal of Applied Clinical Medical Physics 15 (6)

ADC texture—An imaging biomarker for high-grade glioma?

P Brynolfsson, D Nilsson, R Henriksson, J Hauksson, M Karlsson, …

Medical physics 41 (10), 101903

CT substitutes derived from MR images reconstructed with parallel imaging

A Johansson, A Garpebring, T Asklund, T Nyholm

Medical physics 41 (8), 082302

Physiologically Realistic and Validated Mathematical Liver Model Revels Hepatobiliary Transfer Rates for Gd-EOB-DTPA Using Human DCE-MRI Data

Forsgren MF, Dahlqvist Leinhard O, Cedersund G, Lundberg P

PLoS ONE, 2014 Apr 18;9(4):e95700. doi: 10.1371/journal.pone.0095700. eCollection 2014..

Multi-parametric representation of voxel-based quantitative magnetic resonance imaging,

Engström, M, Warntjes, JBM,, Tisell, A, Landtblom AM, Lundberg, P

PLoS One 201, 9(11):e111688. doi: 10.1371/journal.pone.0111688. eCollection 2014.

Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

Skripcak T, Belka C, Bosch W, Brink C, Brunner T, Budach V, Büttner D, Debus J, Dekker A, Grau C, Gulliford S, Hurkmans C, Just U, Krause M, Lambin P, Langendijk J, Lewensohn R, Lühr A, Maingon P, Masucci M, Niyazi M, Poortmans P, Simon M, Schmidberger H, Spezi E, Stuschke M, Valentini V, Verheij M, Whitfield G, Zackrisson B, Zips D, Baumann M
Radiotherapy and Oncology 113, 303-309

Counterpoint: Opportunities and Challenges of a Magnetic Resonance Imaging–Only Radiotherapy Work Flow

T Nyholm, J Jonsson

Seminars in radiation oncology 24 (3), 175-180




Improved quality of computed tomography substitute derived from magnetic resonance (MR) data by incorporation of spatial information-potential application for MR-only radiotherapy and attenuation correction in positron emission tomography

A Johansson, A Garpebring, M Karlsson, T Asklund, T Nyholm

Acta Oncologica 52 (7), 1369-1373

Treatment planning of intracranial targets on MRI derived substitute CT data

JH Jonsson, A Johansson, K Söderström, T Asklund, T Nyholm

Radiotherapy and Oncology 108 (1), 118-122

Bone contrast optimization in magnetic resonance imaging using experimental design of ultra-short echo-time parameters

A Lindström, CD Andersson, A Johansson, M Karlsson, T Nyholm

Chemometrics and Intelligent Laboratory Systems 125, 33-39

Variability in prostate and seminal vesicle delineations defined on magnetic resonance images, a multi-observer,-center and-sequence study

T Nyholm, J Jonsson, K Soderstrom, P Bergstrom, A Carlberg, G Frykholm, …

Radiat Oncol 8 (1), 126

Evaluation of an attenuation correction method for PET/MR imaging of the head based on substitute CT images

A Larsson, A Johansson, J Axelsson, T Nyholm, T Asklund, K Riklund, …

Magnetic Resonance Materials in Physics, Biology and Medicine 26 (1), 127-136

Application of Quantitative MRI for Brain Tissue Segmentation at 1.5 T and 3.0 T Field Strengths

West J, Blystad I, Warntjes JBM, Engström M, Lundberg

PLoS ONE 2013 (8) 1-12.

Brain Characterization using Normalized Quantitative Magnetic Resonance Imaging

Warntjes, JBM, Engström, M, Tisell, A, Lundberg, P

PLoS ONE 8 (8),  :e70864. doi: 10.1371/journal.pone.0070864.

Separation of Advanced from Mild Hepatic Fibrosis by Quantification of the Hepatobiliary Uptake of Gd-EOB-DTPA

Norén B, Forsgren MF, Dahlqvist Leinhard O, Dahlström N, Kihlberg J, Romu T, Kechagias S, Almer S, Smedby Ö, Lundberg P

Eur Radiol 2013 Jan;23(1):174-81. doi: 10.1007/s00330-012-2583-2. Epub 2012 Jul 27.

Procedure for quantitative H-1 magnetic resonance spectroscopy and tissue characterization of human brain tissue based on the use of quantitative magnetic resonance imaging

Tisell A, Dahlqvist Leinhard O, Warntjes JBM, Lundberg P

Magn Reson Med. 2012 Nov 20. doi: 10.1002/mrm.24554. [Epub ahead of print]; 2013, 70 (4) 905-915


Invitationals – presentations and tutoring



5th MRinRT symposium, Sydney, Tufve Nyholm

European School for Medical Physics Expert on Imaging in Radiotherapy, Prague, Stina Svensson


ESTRO, Turin, Joakim Jonsson

ESTRO, Turin, Anders Garpebring

ESTRO, Turin, Tufve Nyholm

ESTRO, Turin, Katrin Riklund Åhlström



2nd Honk Kong Radiographers and Radiotherapists Conference, Hong Kong, Tufve Nyholm

Svensk Onkologisk Förening, Umeå, Tufve Nyholm

Cerro, les Menuires, Tufve Nyholm

RadOnc, Vienna, Tufve Nyholm

NucMed and Onc Kraznoyarsk, Tufve Nyholm

ESTRO, Barcelona, Tufve Nyholm

Siemens-Varian World Summit at ESTRO, Barcelona, Christian Gustafsson

MR-linac meeting, Utrecht, Stina Svensson

MR-guided radiotherapy symposium, Heidelberg, Stina Svensson

Autosegmentation workshop, Toronto, Stina Svensson

3rd international MR in RT symposium, Lund, Stina Svensson

3rd international MR in RT symposium, Lund, Anders Garpebring

ESMRMB, Edinburgh, Patrik Brynolfsson



Hamburger Radioonkologie-symposium, Hamburg, Tufve Nyholm

AAPM, Austin, Tufve Nyholm

Svensk Onkologisk Förening, Eskilstuna, Tufve Nyholm

Svensk Onkologisk Förening, Eskilstuna, Joakim Jonsson

1st Nordic Symposium in Pediatric Proton Therapy, Uppsala, Tufve Nyholm

Siemens-Varian World Summit at ESTRO, Vienna, Gunilla Frykholm

9th MAGNETOM World Summit, Oxfordshire, Mikael Karlsson



ESTRO, Geneva 2013

ACTA Oncologica, Aarhus 2013

Siemens användarmöte, Atlanta 2013

Svensk Onkologisk Förening, Linköping 2013

Siemens Nationella MR-symposium, Malmö, Mikael Karlsson